Bạn vi lòng đọc cho kỷ lại, tất cả đều thuộc nhóm thuốc bạn đang dùng: TDF + 3TC + EFVGửi bởi vietnamboth
dạ theo hướng dẫn thuốc thì không còn ưu tiên nữa đó anh
- There are now five Recommended regimens for antiretroviral therapy (ART)-naive patients—four integrase strand transfer inhibitor (INSTI)-based regimens and one ritonavir-boosted protease inhibitor (PI/r)-based regimen, as listed below:
INSTI-Based Regimens:
- Dolutegravir/abacavir/lamivudine (DTG/ABC/3TC)—only for patients who are HLA-B*5701 negative (AI)
- DTG plus tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) (AI)
- Elvitegravir/cobicistat/TDF/FTC (EVG/c/TDF/FTC)—only for patients with pre-ART CrCl >70 mL/min (AI)
- Raltegravir (RAL) plus TDF/FTC (AI)
PI/r-Based Regimen:
- Darunavir/ritonavir (DRV/r) plus TDF/FTC (AI)
- Two regimens previously classified as Recommended regimens have been moved to the Alternative regimens category, with the rationale stated below:
- Atazanavir/ritonavir (ATV/r) plus TDF/FTC (BI)—Based on the results of a large comparative clinical trial showing a greater rate of discontinuation with ATV/r plus TDF/FTC because of toxicities when compared to (DRV/r or RAL) plus TDF/FTC
- Efavirenz/TDF/FTC (EFV/TDF/FTC) (BI)—Based on concerns about the tolerability of EFV in clinical trials and practice, especially the high rate of central nervous system (CNS)-related toxicities and a possible association with suicidalit
- nguồn http://aidsinfo.nih.gov/guidelines/h...t-guidelines/0
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