Mình đặt Câu hỏi và đượC trả lời như sau:
CDC says 97% by 3 months and other 3% by 6 months. It does not specify the other 3 percent. But on some other resources like this website, states those are the people who have or are on drugs, chemo, cancer, and weak immune system etc. so is that right ? Because i didn't find that info on CDC website. Can you elaborate on that please ? Thankshttp://www.cdc.gov/actagainstaids/basics/testing.html
2) how do you know a 2nd generation test from a 3rd ? My clinic used a "Clear-view HIV 1/2" which he told me was a 3rd generation but on CDC website the same test claims as 2nd generation. http://www.cdc.gov/hiv/pdf/testing_a...hivtesting.pdf
3) Recently my clinic got new FDA approved "Alere Rapid 4th generation test" which i have used it as well. How accurate are they compare to lab based 4th generation test. I heard its not as specific or reliable.
4) Does the 3 month window period apply for all generation antibody test ? Regardless of high-low exposure except those who are on pep ? Or 6 month follow up necessary for everyone ?
5) I have been tested accordingly after 3 months and recently up to 5 months short of 10 days. Two were just regular antibody tests and one was the Alere rapid 4th generation test, all were negative. Is it enough or 6 months required for me ? Only 1 more month left, i am really stressed! last exposure was on 7-15-2015 and last tested was on 12-1-2015 with just a regular antibody test (Clear View HIV 1/2) I don't know what generation because of the conflicting info from CDC.
Thank You for your time! Have a great week!
Answer:
Hello and thanks for reaching out to the AIDS Vancouver Helpline.
It looks like you've certainly done your research and now you've got a few questions you're seeking answers to in order to clarify a couple of things. Nice work! I'll answer your questions in the order you asked them, and we'll start with your question about the CDC guidelines.
1) It isn't that the CDC guidelines are unreliable or outdated, but they do tend to be more conservative than other guidelines. Based on the guidelines we follow in British Columbia, we consider HIV test results to be considered conclusive at 12 weeks post-exposure. As you've read, there are only a few situations where the window period would be extended. These situations are: if you've been on antiviral treatment for hepatitis C, if you are receiving chemotherapy, if you've taken HIV post-exposure prophylaxis, or if you have an immunodeficiency condition. In these scenarios, the time it takes for your body to produce antibodies may be extended, which explains the longer window period. These situations are rare, and so the vast majority of the population can go with the the 12 week (or 3 month) window period.
2) Both 2nd and 3rd generation tests look for antibodies that the body produces in response to the HIV virus. The main difference is that 3rd generation tests are able to detect antibodies earlier than 2nd generation tests. For more information, feel free to check out this website: HIV Clinical Resource. Most available tests in North America are at least 3rd generation. For you, the important thing is that you tested after 3 months, and so by that time it shouldn't make a difference as to whether or not the test was a 2nd generation or a 3rd generation test.
3) As per the CDC, Alere Determine Rapid 4th generation tests are not as sensitive for early HIV infection as lab-based 4th generation tests. (Rapid tests mean they are done in the point-of-care setting and you can get your results almost right away; it doesn't mean that they can detect HIV more rapidly than other tests). Basically, this just means that this test may not be as accurate as a lab-based 4th generation test in the first couple weeks post-exposure, but once you get to the time where you used the test, there shouldn't be much difference between the two. The guidelines we follow in British Columbia suggest that this test, like the 4th generation laboratory test, is conclusive at 12 weeks post-exposure.
4) Yes, regardless of whether the activity you engaged in was high risk or low risk, the 12 week (3 month) window period applies. It is only in the 4 specific cases we talked about in #1 where the window period is extended.
5) Great to hear your test results have all been negative! Based on the guidelines we follow in British Columbia, we would consider your test results to be conclusive (unless you fall into one of the 4 specific cases mentioned in #1). It is ultimately going to be up to you whether or not you decide to test again, but provided you haven't had any possible exposures since July, it's very unlikely that your negative test result from ~5 months post-exposure will change if you were to test again at 6 months post-exposure.
Nghia là: vân Có trường hợp sáu tháng thay đổi nếu nằm trong 4 trường hợp đặC biệt là : sử dụng thuốC điều trị viêm gan B, C. hóa trị, sử dụng pep, và người Có miên dịCh kém.
