Em đang sử dụng pep. Mong muốn được anh chị tư vấn.

[SmileAndLive]

A ơi em lo sợ quá, em vẫn uống pep đúng giờ hôm nay là được 6 viên rồi ạ. A ơi có ai uống pep mà vẫn bị HIV k ạ :(

https://www.aidsmap.com/about-hiv/ho...rophylaxis-pep
The most accurate way to test the efficacy of PEP would be to conduct randomised trials comparing people taking PEP with people not taking PEP. However, this has never been considered to be ethically acceptable as it would involve denying people who have been exposed to HIV a treatment that was expected to be effective. As a result, almost all the evidence on the effectiveness of PEP in humans comes from observational studies, which provide a less robust form of evidence. However, these studies indicate that PEP is highly effective.
In 2016, the Centers for Disease Control and Prevention (CDC) in the United States reviewed six observational studies of PEP use by gay, bisexual and other men who have sex with men. The six studies, from the United States, Australia, the Netherlands and Brazil had been published since 2004.
The latest news and research on PEP

Of the 1535 men who took PEP, 1487 remained HIV negative and 48 men acquired HIV. However, the details of the transmissions that did occur are important.

• In 40 cases, HIV infection was attributed to ongoing risk behaviour after completing PEP. Among these 40 are 35 cases in which seroconversion occurred more than six months after starting PEP. These HIV transmissions are unlikely to be due to a failure of PEP.
• 8 cases are considered to represent potential PEP failures. This equates to 5.2 transmissions per 1000 PEP users (0.5%)

ven among these eight cases it is not certain that PEP failed. In three cases, very few details of the cases were recorded by researchers. Another four were diagnosed with HIV between three and six months after starting PEP, but no information on their sexual behaviour after finishing PEP was reported – it is possible that they acquired HIV due to further risky sex after completing PEP. One case might be due to a strain of HIV that was resistant to a drug included in the man’s PEP regimen.
The CDC identified a further 15 studies in other populations, including adults, adolescents and children. They may have been exposed to HIV through consensual sex, sexual assault, injecting drug use or needlestick injuries, depending on the individual study.
Of the 2209 people who took PEP, 2190 remained HIV negative and 19 were diagnosed with HIV.

• In 18 cases, HIV acquisition could be explained by factors such as poor adherence or ongoing risk behaviour.
• One case was attributed to PEP failure. This relates to a woman who began PEP within four hours of being sexually assaulted and completed the 28-day course, but seroconverted to HIV six weeks after starting PEP.